Lab-on-a-chips

for biological analysis

INTA develops and produces lab-on-a-chips for the detection of several biological analytes as proteins, viruses, bacteria even in body fluids (blood, saliva). The technology is based on nanoacoustics. By using advanced techniques for the immobilization of probe molecules on the surface of the biosensors and thanks to artificial intelligence algorithms for the data analysis, the INTA's products can detect bio-analytes with very high precision and sensitivity on the surface of a small chip. This technology can be applied to several fields as biomedical, environmental monitoring, security, industry, food analysis.

INTA is developing its first product for the diagnosis of traumatic brain injuries with a rapid and portable system for blood analysis.

Video

From a single drop of blood

From a single

drop of blood

All it takes to perform an accurate analysis is a drop of blood, nothing else!

Detect Biomarkers

Our product detects

Biomarkers

  • Proteins/antibodies
  • Viruses (e.g., measles, SARS-CoV-2 spike)
  • Bacteria (e.g., legionella)
  •  Other bio-analytes (e.g., nucleic acids) can be evaluated upon request
Fast and accurate diagnosis

Fast and accurate

diagnosis

The patient receives more precise diagnoses without unnecessary analyzes, but above all faster!

Cost and time reduction

Reduction

of cost and time

Thanks to this new technology it is possible to save expensive and sometimes useless analyzes.

Our publications

Advanced Functional Materials (2022)

Surface-Acoustic-Wave (SAW) Induced Mixing Enhances the Detection of Viruses: Application to Measles Sensing in Whole Human Saliva with a SAW Lab-On-a-Chip

Measles is one of the most infectious airborne viruses worldwide. With a basic reproduction rate between 12–18, this virus is six times more infectious than the SARS-CoV-2 Alpha variant and similar to the SARS-CoV-2 Omicron variant. Even though a cheap and effective vaccine is available, measles is still common in developing countries. To date, sporadic outbreaks are also reported in developed countries, primarily due to non-vaccinated people. This work presents a point-of-care (POC) biosensing device capable of detecting measles virions (MV) in human saliva...


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Biosensors and Bioelectronics (2021)

Glial-fibrillary-acidic-protein (GFAP) biomarker detection in serum-matrix: Functionalization strategies and detection by an ultra-high-frequency surface-acoustic-wave (UHF-SAW) lab-on-chip

Glial-fibrillary-acidic-protein (GFAP) has recently drawn significant attention from the clinical environment as a promising biomarker. The pathologies which can be linked to the presence of GFAP in blood severely affect the human central nervous system...


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IEEE Access (2019)

Full-SAW Microfluidics-Based Lab-on-a-Chip for Biosensing

Many approaches to diagnostic testing remain decades old. Well-established biosensing technologies typically cannot fulfill the requirements....


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Sensors and Actuators: B Chemical (2018)

A Rayleigh surface acoustic wave (R-SAW) resonator biosensor based on positive and negative reflectors with sub-nanomolar limit of detection

Many approaches to diagnostic testing remain decades old. Well-established biosensing technologies (e.g., enzyme-linked immunosorbent assays and radio-immunoassays) typically cannot fulfill the requirements of portability and ease of use necessary for point-of-care purposes...


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Our patents

Priority 10.01.2019 - granted

WO2020144620 - SENSORIZED DEVICE FOR THE ANALYSIS OF A FLUID BY MEANS OF ACOUSTIC WAVES

A method for the detection of analytes within a fluid, said method comprising the steps of prearranging a sensorized device (100) comprising at least one SAW sensor (110), said or each SAW sensor (110) comprising a substrate (115) having an outer surface (IIS') comprising at least one piezoelectric portion...


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